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Lehninger's Fundamentals of Biochemistry. In 3 volumes

299.99 €
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Lehninger's Fundamentals of Biochemistry. In 3 volumes
299.99 €
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This translation of the seventh original edition of this world-renowned textbook, written by talented American scientists and educators, reflects the rapid development of modern biochemistry and includes key advances that help illuminate important aspects of this science.

Volume 1 examines the chemical, physical, genetic, and evolutionary foundations of biochemistry, the structure and functions of various biomolecules and biomembranes, modern methods of their analysis, and new biotechnological products derived from DNA-encoded information, signal transduction systems, and biosignaling mechanisms. Each chapter includes self-assessment exercises.

Volume 2 includes Part II, "Bioenergetics and Metabolism." The book covers general thermodynamic concepts applicable to biological systems, a classification of chemical reactions occurring in living organisms, and a detailed examination of the main metabolic pathways—glycolysis, gluconeogenesis, the pentose phosphate pathway, the citric acid and urea cycles, oxidative phosphorylation, photosynthesis, and carbohydrate biosynthesis in plants; the processes of amino acid, lipid, and nucleotide catabolism and anabolism; and the principles of hormonal regulation and metabolic integration in mammals. Each chapter includes self-assessment exercises.

Volume 3 includes Part III, "Pathways of Information Transmission," brief problem solutions and answers to questions, a subject index covering the material from Volumes 1–3, as well as abbreviations and a glossary. The fundamental dogma of molecular biology and its current understanding are discussed, as well as the processes of transmission and storage of genetic information (replication, transcription, translation, repair, and recombination), chromosome structure, mechanisms of enzymatic processes, the functions of various RNAs in the cell, ribozymes, splicing, alternative splicing, and processing.

Protein biosynthesis, its transport to its destination, and cellular cleavage systems are described in detail, as well as the regulation of gene expression in bacteria and eukaryotes. Each chapter includes examples from medicine, molecular biology, and related fields, as well as engaging exercises and questions.
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